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Pharma giant Eli Lilly also is pushing to get FDA approval for tirzepatide, a diabetes medication, to be added to the weight loss market in the U.S

In the ATTAIN-1 trial of orforglipron, the most common adverse events were nausea (2133% depending on dose), constipation (2129%), diarrhea (2123%), vomiting (1324%), and heartburn

Some researchers find that 8mg provides sufficient results with fewer side effects

I find that for people who have the potential to start a family or to continue their family, it's a very high-risk medication, says Fishman, Thus, the FDA recommends that if you are of child-bearing potential, use a highly-effective method of birth control and talk to your doctor now about weaning off the medication if you consider getting pregnant in the near future

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Sit down and relax the leg muscle completely before injecting